Dr. Christina  Feser  Do image

Dr. Christina Feser Do

1725 Medical Ctr Pkwy Suite 300
Murfreesboro TN 37129
615 934-4100
Medical School: Other - Unknown
Accepts Medicare: No
Participates In eRX: No
Participates In PQRS: No
Participates In EHR: No
License #: 58.003333
NPI: 1902122096
Taxonomy Codes:
207N00000X 208D00000X

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Muir-Torre Syndrome: A Case Associated with an Infrequent Gene Mutation. - The Journal of clinical and aesthetic dermatology
Muir-Torre syndrome is a rare, autosomal dominant genodermatosis characterized by the presence of at least one sebaceous gland neoplasm, associated with an underlying visceral malignancy. Muir-Torre syndrome is believed to be a subtype of Lynch Syndrome. Affected individuals are found to have germline mutations predominantly in DNA mismatch repair gene MSH2, and much less frequently, MLH1. The authors report the case of a 55-year-old woman presenting with multiple cutaneous neoplasms including sebaceoma, basal cell carcinoma, and squamous cell carcinoma; personal history of colorectal and endometrial cancer; and family history of colorectal cancer; found to have a deletion at mismatch repair gene MLH1. It is important to recognize the role of these less common gene deletions in producing the Muir-Torre syndrome phenotype, and consider the correlation of cutaneous manifestations with internal disease. The authors discuss the clinical presentation of Muir-Torre syndrome, methods of diagnosis, and the importance of regular medical surveillance to detect and prevent disease progression in Muir-Torre syndrome patients and their family members.

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1725 Medical Ctr Pkwy Suite 300 Murfreesboro, TN 37129
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