Dr. Ossama  Al Masalmeh  Md image

Dr. Ossama Al Masalmeh Md

501 Madison Ave
Scranton PA 18505
570 432-2383
Medical School: Other - Unknown
Accepts Medicare: No
Participates In eRX: No
Participates In PQRS: No
Participates In EHR: No
License #: MT203181
NPI: 1851654776
Taxonomy Codes:
207R00000X 390200000X

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Prognostic Value of Biomarkers in Acute Non-massive Pulmonary Embolism: A Systematic Review and Meta-analysis. - Lung
Various biomarkers have been evaluated to risk stratify patients with acute pulmonary embolism (PE). We aimed to summarize the available evidence to compare the prognostic value of three most widely studied biomarkers in normotensive patients with acute PE.A systematic literature review of database, including Pubmed, EMBASE and Cochrane, was done. Studies were included if those were done on patients with acute PE and serum troponin or brain natriuretic peptide and N-terminal proBNP (BNP/NT-proBNP) or Heart-type fatty acid-binding protein (H-FABP) assay was done. The primary end point was short-term all-cause mortality. The secondary end points were PE-related mortality and serious adverse events.All three biomarkers were significantly associated with increased risk for short-term all-cause mortality, PE-related mortality and serious adverse events. All-cause mortality: troponin [odds ratio (OR) 4.80; 95 % CI 3.25-7.08, I (2) = 54 %], BNP or NT-proBNP (OR 7.98; 95 % CI 4.34-14.67, I (2) = 0 %); PE-related mortality: troponin (OR 3.80; 95 % CI 2.74-5.27, I (2) = 0 %), BNP or NT-proBNP (OR 7.57; 95 % CI 2.89-19.81, I (2) = 0 %) and H-FABP (OR 25.97; 95 % CI 6.63-101.66, I (2) = 40 %). H-FABP has the lowest negative likelihood ratio (NLR) of 0.17 for mortality followed by high-sensitive cardiac troponin T (hs-cTnT) with NLR of 0.21.None of the biomarker identifies a subgroup of patients who can be managed as an outpatient versus patients who may get benefit from thrombolytics with certainty; however, H-FABP and hs-cTnT showed some promising results and should be investigated further.
Transjugular retrograde cannulation of the portal vein via patent ductus venosus: alternative access for endovascular hepatic interventions. - Journal of vascular and interventional radiology : JVIR
The use of the patent ductus venosus via a transjugular approach to access the portal system for endovascular treatment of hepatic vascular anomalies in three infants is reported. Two patients had an arterioportal fistula, and one had a rapidly involuting congenital hemangioma. All patients underwent arteriography followed by embolization of the vascular anomalies without complications. This alternative route is technically simpler and likely safer than transarterial and transhepatic approaches.Copyright © 2013 SIR. Published by Elsevier Inc. All rights reserved.

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