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Dr. Joseph  Plas  Md image

Dr. Joseph Plas Md

2404 S Locust St Suite 2
Las Cruces NM 88001
505 225-5900
Medical School: Other - Unknown
Accepts Medicare: No
Participates In eRX: No
Participates In PQRS: No
Participates In EHR: No
License #: 99-282
NPI: 1639249816
Taxonomy Codes:
207Q00000X

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Publications

Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors. - Bioorganic & medicinal chemistry letters
The insulin-like growth factor-1 receptor (IGF-1R) plays an important role in the regulation of cell growth and differentiation, and in protection from apoptosis. IGF-1R has been shown to be an appealing target for the treatment of human cancer. Herein, we report the synthesis, structure-activity relationships (SAR), X-ray cocrystal structure and in vivo tumor study results for a series of 2,4-bis-arylamino-1,3-pyrimidines.Copyright © 2011 Elsevier Ltd. All rights reserved.

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2404 S Locust St Suite 2 Las Cruces, NM 88001
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