Docality.com Logo
 
Dr. Maha  Zikra  Md image

Dr. Maha Zikra Md

7300 Sandlake Commons Blvd Bldg-A, Suite# 112
Orlando FL 32819
407 489-9990
Medical School: Other - 1987
Accepts Medicare: Yes
Participates In eRX: Yes
Participates In PQRS: No
Participates In EHR: Yes
License #: ME70379
NPI: 1366425654
Taxonomy Codes:
207RE0101X

Request Appointment Information

Awards & Recognitions

About Us

Practice Philosophy

Conditions

Dr. Maha Zikra is associated with these group practices

Procedure Pricing

HCPCS Code Description Average Price Average Price
Allowed By Medicare
HCPCS Code:77080 Description:Dxa bone density axial Average Price:$147.04 Average Price Allowed
By Medicare:
$60.50
HCPCS Code:99214 Description:Office/outpatient visit est Average Price:$157.81 Average Price Allowed
By Medicare:
$103.34
HCPCS Code:99204 Description:Office/outpatient visit new Average Price:$213.49 Average Price Allowed
By Medicare:
$161.11
HCPCS Code:99215 Description:Office/outpatient visit est Average Price:$187.77 Average Price Allowed
By Medicare:
$139.09
HCPCS Code:99205 Description:Office/outpatient visit new Average Price:$247.18 Average Price Allowed
By Medicare:
$199.89
HCPCS Code:99223 Description:Initial hospital care Average Price:$240.39 Average Price Allowed
By Medicare:
$197.11
HCPCS Code:99213 Description:Office/outpatient visit est Average Price:$110.32 Average Price Allowed
By Medicare:
$69.78
HCPCS Code:99232 Description:Subsequent hospital care Average Price:$107.19 Average Price Allowed
By Medicare:
$69.94
HCPCS Code:76536 Description:Us exam of head and neck Average Price:$155.06 Average Price Allowed
By Medicare:
$118.17

HCPCS Code Definitions

99205
Office or other outpatient visit for the evaluation and management of a new patient, which requires these 3 key components: A comprehensive history; A comprehensive examination; Medical decision making of high complexity. Counseling and/or coordination of care with other physicians, other qualified health care professionals, or agencies are provided consistent with the nature of the problem(s) and the patient's and/or family's needs. Usually, the presenting problem(s) are of moderate to high severity. Typically, 60 minutes are spent face-to-face with the patient and/or family.
99223
Initial hospital care, per day, for the evaluation and management of a patient, which requires these 3 key components: A comprehensive history; A comprehensive examination; and Medical decision making of high complexity. Counseling and/or coordination of care with other physicians, other qualified health care professionals, or agencies are provided consistent with the nature of the problem(s) and the patient's and/or family's needs. Usually, the problem(s) requiring admission are of high severity. Typically, 70 minutes are spent at the bedside and on the patient's hospital floor or unit.
99215
Office or other outpatient visit for the evaluation and management of an established patient, which requires at least 2 of these 3 key components: A comprehensive history; A comprehensive examination; Medical decision making of high complexity. Counseling and/or coordination of care with other physicians, other qualified health care professionals, or agencies are provided consistent with the nature of the problem(s) and the patient's and/or family's needs. Usually, the presenting problem(s) are of moderate to high severity. Typically, 40 minutes are spent face-to-face with the patient and/or family.
99204
Office or other outpatient visit for the evaluation and management of a new patient, which requires these 3 key components: A comprehensive history; A comprehensive examination; Medical decision making of moderate complexity. Counseling and/or coordination of care with other physicians, other qualified health care professionals, or agencies are provided consistent with the nature of the problem(s) and the patient's and/or family's needs. Usually, the presenting problem(s) are of moderate to high severity. Typically, 45 minutes are spent face-to-face with the patient and/or family.
76536
Ultrasound, soft tissues of head and neck (eg, thyroid, parathyroid, parotid), real time with image documentation
77080
Dual-energy X-ray absorptiometry (DXA), bone density study, 1 or more sites; axial skeleton (eg, hips, pelvis, spine)
99213
Office or other outpatient visit for the evaluation and management of an established patient, which requires at least 2 of these 3 key components: An expanded problem focused history; An expanded problem focused examination; Medical decision making of low complexity. Counseling and coordination of care with other physicians, other qualified health care professionals, or agencies are provided consistent with the nature of the problem(s) and the patient's and/or family's needs. Usually, the presenting problem(s) are of low to moderate severity. Typically, 15 minutes are spent face-to-face with the patient and/or family.
99214
Office or other outpatient visit for the evaluation and management of an established patient, which requires at least 2 of these 3 key components: A detailed history; A detailed examination; Medical decision making of moderate complexity. Counseling and/or coordination of care with other physicians, other qualified health care professionals, or agencies are provided consistent with the nature of the problem(s) and the patient's and/or family's needs. Usually, the presenting problem(s) are of moderate to high severity. Typically, 25 minutes are spent face-to-face with the patient and/or family.
99232
Subsequent hospital care, per day, for the evaluation and management of a patient, which requires at least 2 of these 3 key components: An expanded problem focused interval history; An expanded problem focused examination; Medical decision making of moderate complexity. Counseling and/or coordination of care with other physicians, other qualified health care professionals, or agencies are provided consistent with the nature of the problem(s) and the patient's and/or family's needs. Usually, the patient is responding inadequately to therapy or has developed a minor complication. Typically, 25 minutes are spent at the bedside and on the patient's hospital floor or unit.

Medical Malpractice Cases

None Found

Medical Board Sanctions

None Found

Referrals

NPI
Doctor Name
Specialty
Count
1548264534
Cardiovascular Disease (Cardiology)
976
1205934288
Hematology/Oncology
793
1922003854
Cardiovascular Disease (Cardiology)
633
1780798223
Nephrology
548
1396826707
Vascular Surgery
513
1275578734
Family Practice
423
1023003290
Ophthalmology
420
1174519995
Diagnostic Radiology
418
1396722476
Family Practice
406
1942224878
Cardiovascular Disease (Cardiology)
389
*These referrals represent the top 10 that Dr. Zikra has made to other doctors

Publications

Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals. - Scientific reports
The liver is a key organ of metabolic homeostasis with functions that oscillate in response to food intake. Although liver and gut microbiome crosstalk has been reported, microbiome-mediated effects on peripheral circadian clocks and their output genes are less well known. Here, we report that germ-free (GF) mice display altered daily oscillation of clock gene expression with a concomitant change in the expression of clock output regulators. Mice exposed to microbes typically exhibit characterized activities of nuclear receptors, some of which (PPARα, LXRβ) regulate specific liver gene expression networks, but these activities are profoundly changed in GF mice. These alterations in microbiome-sensitive gene expression patterns are associated with daily alterations in lipid, glucose, and xenobiotic metabolism, protein turnover, and redox balance, as revealed by hepatic metabolome analyses. Moreover, at the systemic level, daily changes in the abundance of biomarkers such as HDL cholesterol, free fatty acids, FGF21, bilirubin, and lactate depend on the microbiome. Altogether, our results indicate that the microbiome is required for integration of liver clock oscillations that tune output activators and their effectors, thereby regulating metabolic gene expression for optimal liver function.
A novel liquid chromatographic method with fluorescence detection for quantitation of tadalafil and dapoxetine hydrochloride in pharmaceutical dosage form and human plasma. - Se pu = Chinese journal of chromatography / Zhongguo hua xue hui
Tadalafil (TAD) and dapoxetine HCl (DAP) are recently co-formulated and both show native fluorescence. Therefore, a novel, accurate, specific and sensitive reversed-phase high performance liquid chromatographic method with fluorescence detection was developed and validated for their separation and quantitation in dosage form and human plasma using avanafil as an internal standard (IS). Separation was achieved using isocratic elution within 7.0 min on C18 column and acetonitrile-0.15% triethylamine (40:60, v/v; pH 4) as a mobile phase. The flow rate was 1.0 mL/min and the detection was time-programmed at 330, 410 and 370 nm for TAD, DAP and IS, respectively, after excitation at 236 nm. The linear ranges from 0.01 to 30.00 μg/mL for each drug with the limits of detection of 4.20 and 7.20 ng/mL for TAD and DAP, respectively. The method was validated in accordance to the International Conference on Harmonization (ICH) guidelines and was successfully applied to spiked human plasma with mean recoveries of 98.17% and 98.83% for TAD and DAP respectively.
Terezine derivatives from the fungus Phoma herbarum PSU-H256. - Phytochemistry
Investigation of the fungus Phoma herbarum PSU-H256 isolated from a leaf of Hevea brasiliensis resulted in the isolation of eight terezine derivatives (E-L) together with four known compounds. Their structures were established by analysis of spectroscopic evidence. For terezines E and H, their structures were confirmed by single-crystal X-ray diffraction crystallography. In addition, the absolute configuration at C-7 in terezine E was established by Mosher's method. Terezines K and L were tested for antibacterial, antimalarial, antimycobacterial and cytotoxic activities, but were inactive.Copyright © 2015 Elsevier Ltd. All rights reserved.
Paternal and maternal ages have contrasting associations with self-reported schizophrenia liability. - Schizophrenia research
Older paternal age predicts schizophrenia diagnosis in offspring. If this relationship reflects a pathogenic process, paternal age should predict the expression of subclinical schizophrenia liability (schizotypy). We hypothesized that paternal and maternal ages predict positive, negative, and disorganized features of schizotypy, that family history of psychosis moderates the relationship of paternal age with schizotypy, and that stress sensitivity mediates the relationship of maternal age with schizotypy.Two studies are reported, each of undergraduates (n=500 and n=211) who completed the Schizotypal Personality Questionnaire. The second was designed to replicate and extend the first and included assessment of stress sensitivity.In Study 1, older paternal age and younger maternal age predicted greater positive schizotypy (β=.13 and β=-.19, respectively). Parental ages did not predict negative or disorganized features and family history did not moderate the paternal age association. In Study 2, the same pattern of associations between parental ages and schizotypy components was observed. Additionally, stress sensitivity partially mediated the association of maternal age with positive schizotypy whereas it did not contribute to the paternal age association.The association between older paternal age and schizophrenia extends to self-reported positive features of schizophrenia liability, consistent with the notion that this relationship arises from a pathogenic process, such as de novo mutations. Importantly, younger maternal age was an equally potent predictor of positive schizotypy, with its association partially mediated by stress sensitivity.Copyright © 2015 Elsevier B.V. All rights reserved.
EFFECT OF MELATONIN ON SERUM GLUCOSE AND BODY WEIGHT IN STREPTOZOTOCIN INDUCED DIABETES IN ALBINO RATS. - Journal of Ayub Medical College, Abbottabad : JAMC
It has been demonstrated in experimental animal models that oxidative stress causes persistent and chronic hyperglycaemia, causing reduction in antioxidant defence system, ultimately leading to accumulation of free radicals. This study, was performed to observe the effect of melatonin on serum glucose and body weights in streptozotocin induced diabetes in albino rats.Forty healthy adult male albino rats were included in the study and divided equally into 4 groups for 6 weeks. Group-A was taken as control. Group-B received streptozotocin I/P in a dose of 37 mg/kg body weight. Group-C received 10 mg/100 ml melatonin in drinking water and Group-D received only melatonin.Streptozotocin significantly increased serum glucose and decreased weight in group B animals, whereas in group C, melatonin significantly restored serum glucose but could not restore the body weights reduced by streptozotocin. There was a significant reduction in body weight in melatonin treated group D animals.Melatonin decreases oxidative stress and hyperglycemia, but cannot restore the body weight reduced by streptozotocin. In fact, it further reduces body weight both in diabetic and normal state.
Ecthyma Gangrenosum Caused by Escherichia coli in a Previously Healthy Girl. - Pediatric dermatology
Ecthyma gangrenosum is a characteristic lesion of Pseudomonas aeruginosa sepsis in immunocompromised patients. Only eight cases of ecthyma gangrenosum caused by Escherichia coli have been reported. We report a case of ecthyma gangrenosum due to E. coli without bacteremia in a previously healthy girl.© 2015 Wiley Periodicals, Inc.
[Clinical and sociodemographic characteristics of sudden cardiac death victims in northen Tunisia]. - La Tunisie médicale
The sudden cardiac death remains a major public health problem. This dramatic event has not been well investigated in Tunisia.The aim of this work is to study the epidemiological and socio demographic characteristics of Tunisian victims.We prospectively collected clinical, socio demographic and pathology data of victims of sudden cardiac death occurring in the northern Tunisia from October 2010 to September 2012.The study population included 392 men and 108 women with a mean age of 52,2 + / - 15,8 years. Three quarters of the victims were sedentary, 57,9% were smoker and a family history of sudden death was identified in 9,8% of cases. Half of victims had a primary school education, only 8,4% has a university education, 65,6% of subjects lived in urban areas and 64% of victims were married. The vast majority of deaths had occurred either in a public place (41,4%) or at home (36,6%). The most frequent circumstance of death was at rest (67%). Only 5,1% of victims were transported by emergency medical services and 12,1% by civil protection. Ischemic heart disease was the leading cause of death with 267 cases; however a negative autopsy was denoted in 13,9% of victims.Victims of sudden cardiac death in northern Tunisia were relatively young with a male predominance. Physical inactivity and smoking were the most common risk factors for cardiovascular disease. The majority of victims were married, had an urban origin and a low level of education. Ischemic heart disease was the first etiology of sudden death.
Early expression of local cytokines during systemic Candida albicans infection in a murine intravenous challenge model. - Biomedical reports
Local cytokine production is a significant indicator for disease pathogenesis or progression. Previous studies on cytokine production during systemic Candida albicans (C. albicans) infection were solely on kidney or single cell type interaction with C. albicans. Therefore, the present study aimed to assess the early cytokine expression of various target organs (kidney, spleen and brain) over a 72-h time course during systemic C. albicans infection. The local cytokine profiles of the target organs during systemic C. albicans infection were measured by cytometric bead array and ELISA analysis. The results demonstrated that interleukin-6 (IL-6) and IL-2 were statistically significant (P<0.05) in the spleen at 24 and 72 h post-infection, whereas in the kidney, IL-6 and tumor necrosis factor-α (TNF-α) were statistically significant (P<0.05) at 24 and 72 h post-infection and CXCL-1 and transforming growth factor-β (TGF-β) were statistically significant (P<0.05) at 72 h post-infection. In the brain, IL-6 and TNF-α were statistically significant (P<0.05) at 24 and 72 h post-infection, whereas TGF-β was statistically significant (P<0.05) at 72 h post-infection. These findings demonstrate that host immune responses were varied among target organs during systemic C. albicans infection. This could be important for designing targeted immunotherapy against this pathogen through immunomodulatory approaches in future exploratory research.
Multi-step pathogenesis and induction of local immune response by systemic Candida albicans infection in an intravenous challenge mouse model. - International journal of molecular sciences
Different murine species differ in their susceptibility to systemic infection with Candida albicans, giving rise to varied host immune responses, and this is compounded by variations in virulence of the different yeast strains used. Hence, this study was aimed at elucidating the pathogenesis of a clinical C. albicans isolate (HVS6360) in a murine intravenous challenge model by examining the different parameters which included the counts of red blood cells and associated components as well as the organ-specific expression profiles of cytokines and chemokines. Kidneys and brains of infected mice have higher fungal recovery rates as compared to other organs and there were extensive yeast infiltration with moderate to severe inflammation seen in kidney and brain tissues. Red blood cells (RBCs) and haemoglobin (Hb) counts were reduced throughout the infection period. Pattern recognition receptors (PRRs), chemokines and cytokine transcription profiles were varied among the different organs (kidney, spleen and brain) over 72 h post infections. Transcription of most of the PRRs, cytokines and chemokines were suppressed at 72 h post infection in spleen while continuous expression of PRRs, cytokines and chemokines genes were seen in brain and kidney. Reduction in red blood cells and haemoglobin counts might be associated with the action of extracellular haemolysin enzyme and haeme oxygenase of C. albicans in conjunction with iron scavenging for the fungal growth. Renal cells responsible for erythropoietin production may be injured by the infection and hence the combined effect of haemolysis plus lack of erythropoietin-induced RBC replenishment leads to aggravated reduction in RBC numbers. The varied local host immune profiles among target organs during systemic C. albicans infection could be of importance for future work in designing targeted immunotherapy through immunomodulatory approaches.
A new phenalenone derivative from the soil fungus Penicillium herquei PSU-RSPG93. - Natural product research
One new phenalenone derivative, peniciherqueinone (1), together with five known phenalenone derivatives (2-6), one known anthraquinone (7) and two known acetophenones (8 and 9) were isolated from the soil fungus Penicillium herquei PSU-RSPG93. Their structures were established by spectroscopic evidence. The absolute configuration of 1 was determined by anisotropic effect and electronic circular dichroism spectroscopy. Compound 2 exhibited mild antioxidant activity and is noncytotoxic to Vero (African green monkey kidney fibroblasts) cell lines.

Map & Directions

7300 Sandlake Commons Blvd Bldg-A, Suite# 112 Orlando, FL 32819
View Directions In Google Maps

Nearby Doctors

5979 Vineland Rd Suite 114
Orlando, FL 32819
407 521-1818
7758 Wallace Road Suite E
Orlando, FL 32819
407 718-8933
6645 Vineland Rd Suite 250
Orlando, FL 32819
407 636-6779
9400 Turkey Lake Rd
Orlando, FL 32819
321 435-5500
7009 Dr Phillips Blvd Suite 200
Orlando, FL 32819
407 700-0200
6080 S Apopka Vineland Rd
Orlando, FL 32819
407 517-7083
9430 Turkey Lake Rd Ste 114
Orlando, FL 32819
407 541-1202
7009 Dr Phillips Blvd Suite 150
Orlando, FL 32819
407 639-9665
5940 Turkey Lake Rd
Orlando, FL 32819
407 526-6959
7758 Wallace Road, Ste 6 Certified Pediatrics, In Assoc With Nemours,
Orlando, FL 32819
407 510-0082