Docality.com Logo
 
Dr. Florian  Thompson  Dmd image

Dr. Florian Thompson Dmd

4069 Athenian Way
Los Angeles CA 90043
310 956-6559
Medical School: Other - Unknown
Accepts Medicare: No
Participates In eRX: No
Participates In PQRS: No
Participates In EHR: No
License #: 41797
NPI: 1356537575
Taxonomy Codes:
122300000X

Request Appointment Information

Awards & Recognitions

About Us

Practice Philosophy

Conditions

Medical Malpractice Cases

None Found

Medical Board Sanctions

None Found

Referrals

None Found

Publications

Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. - G3 (Bethesda, Md.)
The Muller F element (4.2 Mb, ~80 protein-coding genes) is an unusual autosome of Drosophila melanogaster; it is mostly heterochromatic with a low recombination rate. To investigate how these properties impact the evolution of repeats and genes, we manually improved the sequence and annotated the genes on the D. erecta, D. mojavensis, and D. grimshawi F elements and euchromatic domains from the Muller D element. We find that F elements have greater transposon density (25-50%) than euchromatic reference regions (3-11%). Among the F elements, D. grimshawi has the lowest transposon density (particularly DINE-1: 2% vs. 11-27%). F element genes have larger coding spans, more coding exons, larger introns, and lower codon bias. Comparison of the Effective Number of Codons with the Codon Adaptation Index shows that, in contrast to the other species, codon bias in D. grimshawi F element genes can be attributed primarily to selection instead of mutational biases, suggesting that density and types of transposons affect the degree of local heterochromatin formation. F element genes have lower estimated DNA melting temperatures than D element genes, potentially facilitating transcription through heterochromatin. Most F element genes (~90%) have remained on that element, but the F element has smaller syntenic blocks than genome averages (3.4-3.6 vs. 8.4-8.8 genes per block), indicating greater rates of inversion despite lower rates of recombination. Overall, the F element has maintained characteristics that are distinct from other autosomes in the Drosophila lineage, illuminating the constraints imposed by a heterochromatic milieu.Copyright © 2015 Leung et al.

Map & Directions

4069 Athenian Way Los Angeles, CA 90043
View Directions In Google Maps

Nearby Doctors

4314 W Slauson Ave
Los Angeles, CA 90043
323 937-7171
4314 W Slauson Ave
Los Angeles, CA 90043
323 937-7171
4314 W Slauson Ave
Los Angeles, CA 90043
323 937-7171
4401 Crenshaw Blvd Suite 300
Los Angeles, CA 90043
323 908-8360
4314 W Slauson Ave
Los Angeles, CA 90043
323 937-7171
4830 Orinda Ave
Los Angeles, CA 90043
323 985-5728
2500 W Florence Ave
Los Angeles, CA 90043
323 786-6600