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Dr. Jing  Zhang  Md image

Dr. Jing Zhang Md

1050 Clove Road
Staten Island NY 10301
718 166-6440
Medical School: Other - 1983
Accepts Medicare: Yes
Participates In eRX: No
Participates In PQRS: No
Participates In EHR: Yes
License #: 210745
NPI: 1356304372
Taxonomy Codes:
207R00000X

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Awards & Recognitions

About Us

Practice Philosophy

Conditions

Dr. Jing Zhang is associated with these group practices

Procedure Pricing

HCPCS Code Description Average Price Average Price
Allowed By Medicare
HCPCS Code:99214 Description:Office/outpatient visit est Average Price:$179.61 Average Price Allowed
By Medicare:
$117.48
HCPCS Code:99213 Description:Office/outpatient visit est Average Price:$125.00 Average Price Allowed
By Medicare:
$79.75
HCPCS Code:G0008 Description:Admin influenza virus vac Average Price:$44.00 Average Price Allowed
By Medicare:
$25.43
HCPCS Code:36415 Description:Routine venipuncture Average Price:$20.00 Average Price Allowed
By Medicare:
$3.00
HCPCS Code:90471 Description:Immunization admin Average Price:$36.75 Average Price Allowed
By Medicare:
$27.71
HCPCS Code:Q2038 Description:Fluzone vacc, 3 yrs & >, im Average Price:$20.00 Average Price Allowed
By Medicare:
$12.11

HCPCS Code Definitions

90471
Immunization administration (includes percutaneous, intradermal, subcutaneous, or intramuscular injections); 1 vaccine (single or combination vaccine/toxoid)
99214
Office or other outpatient visit for the evaluation and management of an established patient, which requires at least 2 of these 3 key components: A detailed history; A detailed examination; Medical decision making of moderate complexity. Counseling and/or coordination of care with other physicians, other qualified health care professionals, or agencies are provided consistent with the nature of the problem(s) and the patient's and/or family's needs. Usually, the presenting problem(s) are of moderate to high severity. Typically, 25 minutes are spent face-to-face with the patient and/or family.
99213
Office or other outpatient visit for the evaluation and management of an established patient, which requires at least 2 of these 3 key components: An expanded problem focused history; An expanded problem focused examination; Medical decision making of low complexity. Counseling and coordination of care with other physicians, other qualified health care professionals, or agencies are provided consistent with the nature of the problem(s) and the patient's and/or family's needs. Usually, the presenting problem(s) are of low to moderate severity. Typically, 15 minutes are spent face-to-face with the patient and/or family.
G0008
Administration of influenza virus vaccine
Q2038
Influenza virus vaccine, split virus, when administered to individuals 3 years of age and older, for intramuscular use (fluzone)

Medical Malpractice Cases

None Found

Medical Board Sanctions

None Found

Referrals

NPI
Doctor Name
Specialty
Count
1376512715
Internal Medicine
417
1710998778
Psychiatry
381
1750371993
Pulmonary Disease
355
1922069467
Dermatology
283
1659392520
Ophthalmology
282
1588721658
Gastroenterology
241
1447227509
Cardiovascular Disease (Cardiology)
238
1700913076
Cardiovascular Disease (Cardiology)
183
1841225273
Diagnostic Radiology
169
1013009349
Nephrology
161
*These referrals represent the top 10 that Dr. Zhang has made to other doctors

Publications

Scalable Transfer of Suspended Two Dimensional Single Crystals. - Nano letters
Large-scale suspended architectures of various 2D materials (MoS2, MoSe2, WS2 and graphene) are demonstrated on nanoscale patterned substrates, with different physical and chemical surface properties, such as flexible polymer substrates (polydimethylsiloxane), rigid Si substrates and rigid metal substrates (Au/Ag). This transfer method represents a generic, fast, clean and scalable technique to suspend 2D atomic layers. The underlying principle behind this approach, which employs a capillary-force-free wet-contact printing method, was studied by characterizing the nanoscale solid-liquid-vapor interface of 2D layers with respect to different substrates. As a proof-of-concept, a photodetector of suspended MoS2 has been demonstrated with significantly improved photosensitivity. This strategy could be extended to several other 2D material systems and open the pathway towards better optoelectrical and nanoelectromechnical systems.
Copper depletion inhibits CoCl2-induced aggressive phenotype of MCF-7 cells via downregulation of HIF-1 and inhibition of Snail/Twist-mediated epithelial-mesenchymal transition. - Scientific reports
Copper, a strictly regulated trace element, is essential for many physiological processes including angiogenesis. Dysregulated angiogenesis has been associated with increased copper in tumors, and thus copper chelators have been used to inhibit tumor angiogenesis. However, it remains unclear whether copper has any effect on epithelial-mesenchymal transition (EMT). Using CoCl2-induced EMT of human breast carcinoma MCF-7 cells, we found that TEPA, a copper chelator, inhibited EMT-like cell morphology and cytoskeleton arrangement triggered by CoCl2; decreased the expression of vimentin and fibronectin, markers typical of EMT; inhibited HIF-1 activation and HIF1-α accumulation in nuclear; and down-regulated the expression of hypoxia-associated transcription factors, Snail and Twist1. Moreover, knockdown copper transport protein, Ctr1, also inhibited CoCl2-induced EMT and reversed the mesenchymal phenotype. In EMT6 xenograft mouse models, TEPA administration inhibited the tumor growth and increased mice survival. Immunohistochemical analysis of the xenograft further demonstrated that TEPA administration significantly inhibited tumor angiogenesis, down-regulated hypoxia-induced transcription factors, Snail and Twist1, leading to decreased transactivation of EMT-associated marker genes, vimentin and fibronectin. These results indicate that TEPA inhibits CoCl2-induced EMT most likely via HIF1-α-Snail/Twist signaling pathway, and copper depletion may be exploited as a therapeutic for breast cancer.
Early treatment of minocycline alleviates white matter and cognitive impairments after chronic cerebral hypoperfusion. - Scientific reports
Subcortical ischemic vascular dementia (SIVD) caused by chronic cerebral hypoperfusion develops with progressive white matter and cognitive impairments, yet no effective therapy is available. We investigated the temporal effects of minocycline on an experimental SIVD exerted by right unilateral common carotid arteries occlusion (rUCCAO). Minocycline treated at the early stage (day 0-3), but not the late stage after rUCCAO (day 4-32) alleviated the white matter and cognitive impairments, and promoted remyelination. The actions of minocycline may not involve the inhibition of microglia activation, based on the effects after the application of a microglial activation inhibitor, macrophage migration inhibitory factor, and co-treatment with lipopolysaccharides. Furthermore, minocycline treatment at the early stage promoted the proliferation of oligodendrocyte progenitor cells (OPCs) in subventricular zone, increased OPC number and alleviated apoptosis of mature oligodendrocytes in white matter. In vitro, minocycline promoted OPC proliferation and increased the percentage of OPCs in S and G2/M phases. We provided direct evidence that early treatment is critical for minocycline to alleviate white matter and cognitive impairments after chronic cerebral hypoperfusion, which may be due to its robust effects on OPC proliferation and mature oligodendrocyte loss. So, early therapeutic time window may be crucial for its application in SIVD.
Group comparison of spatiotemporal dynamics of intrinsic networks in Parkinson's disease. - Brain : a journal of neurology
Recent advances with functional connectivity magnetic resonance imaging have demonstrated that at rest the brain exhibits coherent activity within a number of spatially independent maps, normally called 'intrinsic' or 'resting state' networks. These networks support cognition and behaviour, and are altered in neurodegenerative disease. However, there is a longstanding perspective, and ample functional magnetic resonance imaging evidence, demonstrating that intrinsic networks may be fractionated and that cortical elements may participate in multiple intrinsic networks at different times, dynamically changing alliances to adapt to cognitive demands. A method to probe the fine-grained spatiotemporal structure of networks may be more sensitive to subtle network changes that accompany heterogeneous cognitive deficits caused by a neurodegenerative disease such as Parkinson's disease. Here we tested the hypothesis that alterations to the latent (hidden) structure of intrinsic networks may reveal the impact of underlying pathophysiologic processes as assessed with cerebrospinal fluid biomarkers. Using a novel modelling approach that we call 'network kernel analysis', we compared fine-grained network ensembles (network kernels) that include overlapping cortical elements in 24 patients with Parkinson's disease (ages 45-86, 17 male) and normal cognition or mild cognitive impairment (n = 13), and 21 cognitively normal control subjects (ages 41-76, nine male). An omnibus measure of network disruption, calculated from correlations among network kernels, was correlated with cerebrospinal fluid biomarkers of pathophysiological processes in Parkinson's disease: concentrations of α-synuclein and amyloid-β42. Correlations among network kernels more accurately classified Parkinson's disease from controls than other functional neuroimaging measures. Inspection of the spatial maps related to the default mode network and a frontoparietal task control network kernel showed that the right insula, an area implicated in network shifting and associated with cognitive impairment in Parkinson's disease, was more highly correlated with both these networks in Parkinson's disease than in controls. In Parkinson's disease, increased correlation of the insula with the default mode network was related to lower attentional accuracy. We demonstrated that in an omnibus sense, correlations among network kernels describe biological impact of pathophysiological processes (through correlation with cerebrospinal fluid biomarkers) and clinical status (by classification of patient group). At a greater level of detail, we demonstrate aberrant involvement of the insula in the default mode network and the frontal frontoparietal task control network kernel. Network kernel analysis holds promise as a sensitive method for detecting biologically and clinical relevant changes to specific networks that support cognition and are impaired in Parkinson's disease.© The Author (2015). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Prediction of short term re-exacerbation in patients with acute exacerbation of chronic obstructive pulmonary disease. - International journal of chronic obstructive pulmonary disease
The objective of the study is to develop a scoring system for predicting a 90-day re-exacerbation in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD).A total of 176 consecutive hospitalized patients with AECOPD were included. The sociodemographic characteristics, status before acute exacerbation (AE), presentations of and treatment for the current AE, and the re-exacerbation in 90 days after discharge from hospital were collected.The re-exacerbation rate in 90 days was 48.9% (86 out of 176). It was associated with the degree of lung function impairment (Global initiative for chronic Obstructive Lung Disease [GOLD] grades), frequency of AE in the previous year, and parameters of the current AE, including pleural effusion, use of accessory respiratory muscles, inhaled long-acting β-2-agonists, inhaled corticosteroids, controlled oxygen therapy, noninvasive mechanical ventilation, and length of hospital stay, but was not associated with body mass index, modified Medical Research Council scale, or chronic obstructive pulmonary disease assessment test. A subgroup of ten variables was selected and developed into the re-exacerbation index scoring system (age grades, GOLD grades, AE times in the previous year, pleural effusion, use of accessory respiratory muscles, noninvasive mechanical ventilation, controlled oxygen therapy, inhaled long-acting β-2-agonists and inhaled corticosteroids, and length of hospital stay). The re-exacerbation index showed good discrimination for re-exacerbation, with a C-statistic of 0.750 (P<0.001).A comprehensive assessment integrating parameters of stable chronic obstructive pulmonary disease, clinical presentations at exacerbation, and treatment showed a strong predictive capacity for short-term outcome in patients with AECOPD. Further studies are required to verify these findings.
Optomechanically-induced transparency in parity-time-symmetric microresonators. - Scientific reports
Optomechanically-induced transparency (OMIT) and the associated slowing of light provide the basis for storing photons in nanoscale devices. Here we study OMIT in parity-time (PT)-symmetric microresonators with a tunable gain-to-loss ratio. This system features a sideband-reversed, non-amplifying transparency , i.e., an inverted-OMIT. When the gain-to-loss ratio is varied, the system exhibits a transition from a PT-symmetric phase to a broken-PT-symmetric phase. This PT-phase transition results in the reversal of the pump and gain dependence of the transmission rates. Moreover, we show that by tuning the pump power at a fixed gain-to-loss ratio, or the gain-to-loss ratio at a fixed pump power, one can switch from slow to fast light and vice versa. These findings provide new tools for controlling light propagation using nanofabricated phononic devices.
[Soluble of Metals within TSP in Shanghai]. - Huan jing ke xue= Huanjing kexue / [bian ji, Zhongguo ke xue yuan huan jing ke xue wei yuan hui "Huan jing ke xue" bian ji wei yuan hui.]
The dissolution of metals within aerosol particles is meaningful to evaluate the bioavailability and mobility of metals. Total suspended particles (TSP) samples were collected in Shanghai. We extracted the water soluble and acid soluble (pH = 2) metals by the mini-recirculation-leach-system and measured their concentrations by the high resolution inductively coupled plasma mass spectrometry. The dissolution kinetics were rapid, the maximum solubility of metals could be reached in a few minutes. Overall, the average water-soluble concentrations were low for Co, Cr, Cd, V and Ni, median for Cu, Pb and Mn and high for Fe, Al, Zn and Mg. Combine the soluble metal concentrations with the back trajectory, the original air mass had significant impacts on water soluble metal concentrations. The water solubility and acid solubility were different for various metals, the water solubility of Fe was the lowest (2.0%), others followed an order: Al, Cr, V, Pb, Co, Ni, Cu, Cd, Mn, Mg, Zn. The metals' solubility was increased with the decrease of the solvent pH value. While the chemical speciation of metals was the internal cause of metals' solubility, the metals' ionic potential and the water solubility was negatively correlated.
Calcium Carbonate Nanoplate Assemblies with Directed High-Energy Facets: Additive-free Synthesis, High Drug-Loading and Sustainable Releasing. - ACS applied materials & interfaces
Developing drug delivery systems (DDSs) with high drug-loading capacity and sustainable releasing is critical for long-term chemotherapeutic efficacy, and it still remains challenging. Though the high-energy facets exhibit active physicochemical properties than regular counterparts, they have been rarely explored for a DDS. Herein, a regular assembly of vaterite CaCO3 nanoplates with exposed high-energy {001} facets has been synthesized via a novel, additive-free strategy. The product shows a high doxorubicin-loading capacity (65%); the best of all the CaCO3-based DDSs so far. Also, the product's sustainable releasing performance and its inhibition of the initial burst release, together, endow it with long-term drug efficacy, which is proposed to be the electrostatic interaction between the high-energy {001} facets and the drug molecules. The work may shed light on exposing directed high-energy facets for rationally designing of a drug delivery system with long-term efficacy.
Determination and Method Validation of the New Sulfone Fungicide 2-(4-Fluorophenyl)-5-Methylsulfonyl-1,3,4-Oxadiazole in Tomato and Soil by UPLC in Field Trial Samples from Guizhou Province, China. - Bulletin of environmental contamination and toxicology
A new method was developed and validated for the determination of 2-(4-fluorophenyl)-5-methylsulfonyl-1,3,4-oxadiazole (jiahuangxianjunzuo, JHXJZ) by ultra-performance liquid chromatography equipped with photo-diode array detector. JHXJZ from tomato and soil was extracted with ethyl acetate without further cleanup. The limits of detection and quantification of JHXJZ were 0.0083 and 0.025 mg kg(-1) in tomato, 0.0017 and 0.005 mg kg(-1) in soil, respectively. The average recoveries of tomato and soil were studied at three spiked levels and ranged from 84.51 % to 101.30 % and 85.30 % to 101.53 %, respectively, with relative standard deviations of 2.61 %-4.13 % and 1.21 %-4.80 %, respectively. The results indicated that the reported method could meet the requirement for the analysis of JHXJZ in trace amount in tomato and soil.
Predictors of surgical outcome in cervical spondylotic myelopathy: focusing on the quantitative signal intensity. - European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
The association between intramedullary increased signal intensity (ISI) on T2-weighted magnetic resonance imaging and surgical outcome in cervical spondylotic myelopathy (CSM) remains controversial. The purpose of this study is to assess the impact of quantitative signal change ratio (SCR) on the surgical outcome for CSM.The prospective study included 108 consecutive patients who underwent surgical treatment for CSM. The Japanese Orthopaedic Association (JOA) score and recovery rate were used to evaluate clinical outcomes. JOA recovery rate less than 50 % was defined as a poor clinical result. The SCR was defined as the signal intensity at the level of ISI or severely compressed cord (in cases with no ISI) divided by the signal intensity at the C7-T1 disc level. Age, sex, body mass index, duration of symptoms, surgical technique, preoperative JOA score, levels of compression, preoperative SCR, preoperative C2-7 angle, preoperative C2-7 range of motion were assessed.Forty patients (37.0 %) had a recovery rate of less than 50 %. Multivariate logistic regression analysis revealed that a higher preoperative SCR and a longer duration of symptoms were significant risk factors for a poor clinical outcome. Receiver operating characteristic (ROC) curve analysis showed that the optimal preoperative SCR cutoff value as a predictor of poor clinical result was 1.46. The area under the ROC curve of preoperative SCR for predicting a poor surgical outcome was 0.844.Preoperative SCR significantly reflected the surgical outcome in patients with CSM. Patients with SCR greater than or equal to 1.46 can experience poor recovery after surgery.

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