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Dr. Benjamin  Francois  Md image

Dr. Benjamin Francois Md

605 Ives Dairy Rd Apt 205G
Miami FL 33179
786 871-1876
Medical School: Other - Unknown
Accepts Medicare: No
Participates In eRX: No
Participates In PQRS: No
Participates In EHR: No
License #: ACN596
NPI: 1306241286
Taxonomy Codes:
208D00000X

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Nanoaggregates of biodegradable amphiphilic random polycations for delivering water-insoluble drugs. - Biomacromolecules
Cationic amphiphilic random copolyesters were obtained by copolymerization of 5-Z-amino-δ-valerolactone and ε-caprolactone. The amino content of the final copolymers was controlled by the polymerization feed ratio and was in the range 10 to 100%. Copolymers solubility and aggregation behavior was assessed by conductometric and zeta potential analyses. A critical aggregation concentration of ca. 0.05% (w/v) was found for all water-soluble copolymers that formed nanoaggregates. Two populations were found to be present in equilibrium with hydrodynamic diameters in the range of 30-50 and 100-250 nm. The capacity to use the amphiphilic and cationic character of the nanoaggregates to encapsulate highly hydrophobic compounds was further investigated. Finally, copolymers hemo- and cytocompatibility were evaluated by hemagglutination, hemolysis, and cells proliferation tests. The results showed that the proposed cationic amphiphilic random copolyesters are biocompatible.

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605 Ives Dairy Rd Apt 205G Miami, FL 33179
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Nearby Doctors

1380 Ne Miami Gardens Dr Suite 260
305 452-2675
1610 Ne Miami Gardens Dr
N Miami Beach, FL 33179
305 406-6016
850 Ives Dairy Rd Ste T63
305 549-9399
19501 Ne 10Th Ave # 305
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1380 Ne Miami Gardens Dr Suite 209
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305 457-7575
1021 Ives Dairy Rd Suite 119
305 908-8590
1770 Ne Miami Gardens Dr Unit 1
305 494-4141
1610 Ne Miami Gardens Dr
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305 406-6016
1486 Presidential Way
305 903-3888
1011 Ives Dairy Rd Building 2 Suite 208
305 530-0098